I have been having very good luck running Premeire Pro CS5.5 on my Dell XPS Studio (8 gig of ram) with one 2TB drive in it but running most of the jobs off of my 8TB Netgear RAID box. I am thinking about putting another 2TB drive inside the computer and use it as a scratch drive only. Will that improve anything in the performance? The only issue I have now is some slowing when I drop 30 minutes or more of video on a timeline. That is not a big deal but I'd like to have a better idea about if a dedicated scratch drive will step performance or reliability up in any way.
I can confirm a nice, fast drive (I used a 2TB WD Cavier Black 7200 RPM drive as my scratch and media cache drive) yields noticeable improvement over those files residing on the system drive or the project drive.
When I RAIDED my project drive, however, the improvement was not so noticeable. I can say that there was more fluctuation in performance putting all on the one RAIDed drive, though. (ie, Renders showed more consistent high CPU utilization, but utilization tended to dip up and down more).
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