Recently I have had a problem with Lightroom over saturating the blues in the skys of my photos. I start with a RAW file from my Canon 1Ds Mark 3. I start processing it in Lightroom and then send it to Photoshop CS5 as a TIFF to do more editing. The file is saved as a TIFF and appears in the lightroom catalog. In lightroom the skys are now highly saturated, much more than in CS5. I can view the Tiff file in the Windows Preview window and it looks the same as in CS5. If I use lightroom to export to a JPG, the JPG is saturated just like the TIFF appears in Lightroom. Windows Preview shows the JPG highly saturated just like it looks in Lightroom. This problem started in Lightroom 3.6 and has continuted in Lightroom 4. I first noticed it in February 2012. I am using the ProRGB color space when opening it if CS5 and as the workspace in Photoshop CS5. It makes no difference if I save the files in 16 bit color or 8 bit color. Color Management Policies in CS5 are set to Preserve Embeded Profiles. I have tried uninstalling and reinstalling both LR4 and CS5, but that had no effect.
These 2 screen captures show how the blues became more saturated in Lightroom after being edited in Photoshop. Since I do not have Camera RAW 7, I tell Lightroom 4 to render in Lightroom and send a TIFF to CS5. Can anyone tell me what is causing the shiff in the blues?
Lightroom version: 4.0 
Adobe Photoshop Version: 12.0.4 (12.0.4x20110407 [20110407.r.1265 2011/04/07:02:00:00 cutoff; r branch]) x64
Operating system: Windows 7 Business Edition
Version: 6.1 
Application architecture: x64
System architecture: x64
Physical processor count: 4
Processor speed: 2.6 GHz
Built-in memory: 8190.5 MB
Real memory available to Lightroom: 8190.5 MB
Real memory used by Lightroom: 784.5 MB (9.5%)
Virtual memory used by Lightroom: 762.4 MB
Memory cache size: 31.7 MB
System DPI setting: 96 DPI
Desktop composition enabled: Yes
Displays: 1) 1920x1200
Graphics Card: Nvidia GeForce8800 GTX
Video Memory : 731 MB
I checked the HSL sliders in LR and you are right they were off. But, why are the sliders changing like that? I have discovered that it has nothing to do with CS5 at all. I exported a RAW file from LR4 that I had done no editing at all to, to a TIFF file and got the same problem. The HSL sliders are off and blues are over saturated. This does not happen when I export the RAW file to PSD or JPG, so far only to TIFF. Am I missing something. Why is this happening? I have been using Lightroom since version 1 and have use versions 2 and 3 as they came out, but I never had this problem until this year. Is this a bug? If so, it began in version 3.6. I bought version 4 hoping it would fix it, but it didn't.
Like I said, the Develop defaults for Tiff files have been modified. Whether you did it on purpouse or by mistake, or something got corrupted — I don't know.
To restore, select a Tiff file, go to Develop module and click Develop>Set Develop Default>Restore Adobe defaults. From now on, all new Tiffs should look right.
You may need to reset HSL sliders for the older Tiffs.
Thank you. That solved the problem. I have never knowingly changed the defaults, so I don't know how it changed. The command that that you gave is not one I had ever used and so, was not familiar with it. Thank you agian.