Yes, I understand that. I'm trying to first establish whether the problem is with PSE or your scanner. Go to your username>library>preferences and delete:
com.adobe.PhotoshopElements.plist
Adobe Photoshop Elements 10 paths
Adobe Photoshop Elements 10 settings
Repair permissions and try again. That user library is hidden in lion. To see it. click the Go menu in the Finder and hold down the option key. It will appear below the little house for your user account.
Also check the scanner manufacturer's website to see if there is a TWAIN driver for that model that you need to install.
