I'm having trouble with getting quotation marks to display correctly, they look like 2 stacked >> symbols. They change slightly depending on what font I'm using, but they all ride at the base of the text. I cannot acheive normal looking curly or staight quotes at all. I have tried switching smart quotes on and off in the preferences, restarting, etc. I've noticed this problem in the past, but I thought it was the font I was using. The same thing happens with Times New Roman. I'm running an up to date version of PSextended CS5, 64bit on win 7 64. Any help would be greatly appreciated!
Not sure if this is where you looked, but check the overall Windows settings as follows:
Click Start and type Language in the search box. When Region and Language comes up, click it.
Look through all the tabs to ensure everything's set as expected.
Outside of finding something unexpected in there, it's never a bad idea to try resetting the Character tool, or even the Photoshop overall preferences. To reset the Type Tool, select the T tool, then right-click in the T tool icon in the options area: