Thanks. I would first try uninstalling via control panel and then disabling your antivirus/antimalware software and reinstalling. Be sure to save the download, not just run it, so you will have it in the future for reinstalling if necessary.
After doing it you need to not use the program the next time you start it up until the panels repopulate. If you don't see thumbnails in the effects panel, it's too soon, so I'd delete it again and try that.
Just delete these two files -- they're in the hidden "\ProgramData" directory, so you'll need to temporarily change your folder options to show hidden files.
Start PSE, and wait while it automatically rebuilds those database files.
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