Hello,
I haven't had a problem in the past with this. I can typically watch a full screen video on one monitor while working with another application in a second monitor. However, yesterday, this suddently stopped working for me, and I can't find any place to change the settings to get this to work again.
I'm using 64-bit Windows 7, in Google Chrome v21.0.1180.60, with Adobe Flash 11.3.31.222.
I was also having the same problem and this worked for me. In your status bar type Chrome://plugins Next hit the "+ details" button on the far top right of the page. There should be 3 files under Flash. You need to disable PepperFlashplayer.dll and Flash ver 11.3. Restart Chrome and it should work like you need it to. Hope this helps till someone figures out a real fix.
I'd like to recommend you open a bug report on this over here: https://code.google.com/p/chromium/issues/list
I ran into two different problems using the pepper player in chrome (11.3.31.222). The first was it leaving full screen when focus was removed, the second was that it always played on my primary (second) monitor even through my browser was positioned in my first or third monitors.
Balrog14's suggestion is the only thing that has worked for me. None of the other suggestions including openning a bug report has produced any results or responses from adobe.
Chrome://plugins
Disable only 11.3.31.222
Even though adobe tried to release this 'fix' for another issue, it seems to have caused another issue.
North America
Europe, Middle East and Africa
Asia Pacific