Thanks Jeff for the reply.

I overlooked this indexing. Likely because there's not much happening. The number 506 never changes and there is no harddisk activity. But isn't this only for use of the seach bar?

Other thing is That I've already worked with it in CS6 and it all went fine then (and this was after deleting all cache files).

The wave plots do show up now by the way after a third time opening.

Update: The audio also randomly mutes now.

That brings me to the belief that premiere is only using 1 CPU core, since the cpu is at 12% all the time. That could also explain the hanging after trying to properly close this project. For the rest I can do whatever I want on the computer, open Photoshop and/or any other appilcation(s) without a problem.

Thanks Bill for your input.

The HDD has 558GB of free space.

I specifically let the program load the project without touching anything. Then it seemed to be ready (HDD stopt loading files and Premiere even showed a video still this time. But when I pressed spacebar to play screen went black and only audio started to play. Instantly though.

Only virus software installed is Microsoft Security Essentails. But at first this project worked, and it always worked in CS5 so that gives me the conclusion someting's gone wrong with Premiere CS6.

Update: I re-opended the project once more and directly closed the the two open sequence windows and this seems to help somehow. It's now re-creating all 500+ peak files again, though I did not delete those yet. I've read somewhere that this was a common bug of Pr CS5, when you enable 'Save cache files next to originals'. But I luckily did not have this problem in CS5. Apart from that, you'd expect they've fixed a bug this immensly stupid in CS6.

While I've been writing this Premiere has stopped again with generating peak files so closing the sequence windows did not help. And of course it hangs again when trying to close the project.

So.. The coming week became several months, but I finally picked this up again.

I got it working now by deleting all *.pek and *.cfe files, and let Premiere regenerate all those files on the internal cache folder, using up 416GB of working space. Which I have to say again, it makes no sense at all to dump files from all your projects in one big folder. But well, if that's the only way to get Premiere function normal I guess I have no choice.

BUT... Now yet another problem is introduced. Some clips have frames mixed up, or part of another frame is visible. Also after exporting! It's like the first frame of a cut is shown again after 1 second. But this seems to slowly go away as I keep working on the project. Like later on only half the frame is f***ed up instead of the whole frame. I can move the clip around, edit it in all ways but the broken frame remains. I am so finished with this program.

By the way did I ever mention why "- The project contains cuts of over 124 hours of DVD video and additional 5.1 audio exports that are linked to the videos again."?

That's because Premiere gave me stuttering audio with the original *.VOB audio.