Darn, this doesn't work for me. I've seen many other suggestions (clear cache, reduce number of cached file, etc.) in other posts - all seem to work for some people but i haven't found one that works every time for me except to logoff the administrator TWICE - this is foolproof but is a real pain to do every time you want to preview your file.
Any updates on this? I'm now using DW CS5 and it's still happening (CF8). I have to click "Clear Template Cache Now" within CF Admin 2-3 times just to save the CSS file so that I can preview it (not very productive). I've also checked that "Save Class Files" is NOT checked and all other option (under Server Settings - Caching) are also unchecked.
I'm convinced it's DW locking the files and not CF as I can made changes to the CSS file and save them in NotePad or Eclipse without a problem - BUT I like to use DW.
Okay, so now a problem that was originally noted in 2006 is still plaguing us in 2012. I have tried all the fixes recommended and still cannot get it to work. I want to use Dreamweaver for my development efforts but will switch to Eclipse if I can't find a solution. I have changed all the settings in my ColdFusion administrator and even deleted the caches but still cannot edit a css file in Dreamweaver. What is up with this issue?