I just encountered this same error. It has wasted 6 hours and 6GB of my download quota. After everything has been downloaded, the error pops up under the progress bar and nothing can be done. Clicking the Reset product download button produces a popup asking if I want to continue the download, but clicking yes doesn't do anything.

I'm going to re-download everything again with the direct links. Can I suggest giving us the option, directly on the trial page, to download direct or use the download manager? The Adobe Download Assistant obviously wasn't tested enough before it was deployed.

Not an answer, but the same question and a terrible experience with technical support.

I am running a Win 7 64-bit machine with 16GB ram and twin terrabyte drives (OS and programs on one, data on the other). I'm downloading CS6 Design Standard.

After downloading and installing the Download Assistant, I download the files. After 2-3 hours, it gets to 100% and gives the 101 error upon extracting. I've tried extracting it to both drives (never the applications or program folders) - both of which have more than 700GB available and no permissions issues. I have MS Security Essentials disabled. I have tried twice to delete everything, then used Revo to uninstall the Download Assistant, rebooted, and reinstalled. Every single time, I get the same issue. I started a direct download, but it was looking like it would take twelve hours to download, so I decided to call Tech Support.

After spending a total of almost an hour on hold to get Technical Support, and about 20 minutes talking with Technical Support, the guy told me he had never heard of the problem persisting to that degree. He then advised me to disable all startup programs and services (except MS), reboot in safe mode. I thought he was just trying to troubleshoot some issue, but then he says he wants me to download the file that way. The guy got all ratty when I said I can't have my main computer running in safe mode with all the services disabled during business hours. Upon trying to get my computer back to normal, it uninstalled a bunch of drivers, and I had to go back to a restore point. Not your problem, but what a pain in the bum.

I'm now trying it on my laptop (W7 64-bit 8GB ram) with minimal stuff running and Security Essentials disabled, but I'm not hopeful.

At this point, I have burned through half of my monthly bandwidth in two days downloading and re-downloading the same package. I don't go through that much most months! This has been an incredible disappointing, frustrating experience.

Has anyone yet figured out what is causing this issue on computers that don't have space or permission problems? Is spending half a day doing a direct download the only workaround?

i also have a big problem with error 101... it took many hours to download and in the last minute it pops up in the download assistent and says error 101 check for available disk space and try downloading it again i dont know what file i originaly downloaded it too but i would like to start working on it as soon as possible how can i get more disk space. where is that? i dont understand any of what it is sayin

Very well.  This is waaaaaay too complicated and the entire process is a fail, even if we do eventually get to download the trial.  What is Adobe thinking?  We should not be expected to concern ourselves with checksums and such.  Serve your customers, Adobe.

Update: 

I removed and reinstalled the downloader, and made sure I made a new folder for the download.  This did work.  So thanks to Vikrant.  However, I was already signed into my Adobe ID...and the installer told me to sign in again, which I did, and was then told my login info was wrong!  So, I had to create a new ID.

I sympathize with the people at Adobe who are having to deal with unhappy customers....or in this case, unhappy potential customers.  But something is clearly amiss in this process.  It should not be this difficult!

so have exit from it problem? Except download again?

PLEASE PLEASE Help me!

I am trying to download the CS6 Trial...I downloaded the assistant...it is acting crazy and gives me errors...is there away to uninstall everything and start from scratch?

this is april 2013. and this problem still consists, download the manager, then the direct file, the files keep coming back corrupted. adobe youre cool and all, but fix this problem. i have fresh windows 7 installed after reinstallng it again.

i have lots of space and permission isnt the issue.

This was the answer for me. It only took me 20hrs before I found this post, Nice one Rawcookiez!