May i know the version of MAC you have?
Have you tried the same using the root user, If not, you can try that and check. http://support.apple.com/kb/ht1528
Start in Safe Boot mode | Mac OS X : http://helpx.adobe.com/x-productkb/global/start-safe-boot-mode-mac.htm l
Repair Disk Permissions from Utility->Disk Utility
If still same issue, try re-installing Acrobat X and check.
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