If you are using Mac OS X 10.8.2, I and others have had a great amount of difficulty, and have a list of applications that do not upgrade. One fellow did find success after he deleted everything that had 'adobe' in the file or folder names... I've not had the time to test out that processes, as I do have a CS5 setup that I use as a 'backup'... but perhaps I'll trash the entire Adobe installation, both in your 'user account' ~/Library... but also the system /Library... paths.
U44M1P7 is a very generic error and only indicates that the installation has failed. Please try downloading the updates directly from the product update page at http://www.adobe.com/downloads/updates/. If you continue to face difficulties then you will need to look at your installation logs to determine the exact cause of the installation failure. You can find more details at Installation failed. Error U44M1P7 | Updates - http://helpx.adobe.com/creative-suite/kb/error-u44m1p7-installing-upda tes-ccm.html.