LR 4.3 does not open the selected photo. It opens the PREVIOUSLY selected photo.
What do you do when you select the adjustment tools, but only the plus cursor appears,
meaning every click expands the image, no adjustments made. Or when I send an
adjusted nef photo to PS as smart objet, but it looks different in PS? Or when I "pick"
a photo but no flag appears?
Try deleting your preferences file