I have CS6 on a Mac and have had it since it was offered with no problems. Today it won't open and I get the message that I should purge the cache in Preferences. So I am doing that, but it just keeps cranking away and nothing happens. It is stuck there. Force Quit doesn't indicate a problem.
Quit Bridge, from user library (NOT system and root library) preferences folder find and delete the Bridge5.plist file manual. Do this also in same user library caches folder (Caches/Adobe/Bridge CS6) and in here find and the folder called 'cache' and drag it to the trash.
restart Bridge holding down option key and choose reset preferences, then try again.