I recently upgraded to Adobe Acrobat XI pro using creative cloud. I can open pdfs on disc but not on line - using safari mac
What exactly happens in Safari when you click on a link to a PDF (here's one to test: http://www.adobe.com/security/pdfs/riskcompliance_faq.pdf )
Any messages, please give exactly (or a screen shot).
Go to: Mac HD/Library/Internet Plugins
Trash the AdobePDFViewer.plugin and AdobePDFViewerNPAPI.plugin files
Empty the trash. Relaunch Safari
PDFs should open with no trouble.