As with all unexplainable Photoshop-problems You might try trashing the prefs (after making sure all customized presets like Actions, Patterns, Brushes etc. have been saved and making a note of the Preferences You’ve changed) by pressing command-alt-shift on starting the program or starting from a new user-account.

System Maintenance (repairing permissions, purging PRAM, running cron-scripts, etc.) might also be beneficial.

I have the same problem. Waiting for a solution as well.

Same issue here!  All my permissions seem correct.

I just confirmed that the Adobe installer had set all of the CS5 settings subfolders in ~/Library/Preferences to have an owner of "System". I did not have any access to the folders.

Changing the owner of the folders to my user account fixed the access for all of the CS5 apps.

Thanks for the tip.

I'm using a brand new MBP 15" Core i7. I started with a fresh 1TB drive and my OS was cloned from my earlier MBP and then upgraded to 10.6.3 from the restore disks that came with the MBP. Yes, I use Time Machine, but did not restore from it in this case.

The OS on my MacPro was also migrated from my MacBookPro.

I was running CS4 previously on my MacBookPro.

Got the MacPro and transferred all info including CS4, everything worked peachy.

Purchased CS5.

Downloaded and installed CS5.

*I'm not sure exactly which OS version was on at the time of migration as I always keep both computers updated via software update.  As of CS5 install time, both computers were running 10.6.3.

Not sure if that helps?

ETA: Mine is not the trial version.

HERE'S THE FIX:

Navigate to /Users/YOURUSERNAME/Library/Preferences/Adobe Photoshop CS5 Settings

Select that file File>Get Info

At the very bottom under permissions, hit the + icon.

Add your user name from the list that pops up.

Highlight the user just added.

Click the gear icon to the right of the +/-

Choose make owner.

Click the gear icon again and choose apply to folder contents.

Open Photoshop.

That should do the trick!

Yeah, I think the installer is the culprit.

If I go into the ~/Library/Preferences folder and create a new subfolder, it get assigned the correct privileges with me as the owner every time. It's only the CS5 folders created by the Adobe Installer that have a different owner.

That is what I tried earlier and it worked...sorta...I no longer get the "can't save settings" error but now PS won't quit. I have to force quit. If I open in 32 bit mode it quits fine but not in 64 bit mode. I have added no extensions or 32 bit plugins.

I can confirm that on both my machines "EVERYTHING related to CS5 has its permissions set to 'system'. This includes all the apps, their folders and other files, everything."

I'd sure like to know how permissions should be set and if these settings are wrong I sure hope Adobe figures out how to fix this. Quite frankly this is more than a bit disappointing (to put it politely and mildly).

I should add that I have very vanilla flavored machines. I'm no power user, I don't screw around moving files around, and I haven't even loaded any beta apps. I'm running 10.6.3 with NO Time Machine anything and I have no OS X permissions issues.

Thanks. I was 99% sure that should be the case......

To summarize here are the items that I changed permissions on. I made myself the owner and applied changes to all enclosed items. Then I deleted system permissions. I made no changes to the root level library items. I don't know if I've missed anything but so far everything seems to be working fine.

Application Folder:

Adobe Bridge CS5 (folder)

Adobe Device Central CS5 (folder)

Adobe Extension Manager CS5 (folder)

Adobe Media Player (folder)

Adobe Photoshop CS5 (folder)

User/Library/Preferences folder:

Adobe (folder)(not sure but this may have been correct)

Adobe Photoshop CS5 Settings (folder)

Adobe Save for Web 12.0 Prefs

User/Library/Application Support Folder:

Adobe (folder)

User/Library/Caches Folder:

Everything was correct.

Highlight the file or folder. Get Info and then unlock the sharing and permissions pane. Highlight your user name and if the Make (user name) the owner is grayed out then you're already the owner..

ouch, thi has got to hurt!

I thought i'd try the trial and see how it looked. Shame I can't get any of of themaster suite to work properly.

Dreamweaver won't even boot!

Great job!

thanks, it really helps.I wounder if your workspaces is unlocked now?

cos I still have problem with saving a workspace. there error appears with message:"could not apply command because of programm error" or smth like that...

thanks!

  I'm glad I read this post. Maybe you could get back to the thread with an update when the installer is fixed. I'm not going to order till I hear, this will happen to me for sure.

Thanks, Bob-