I'm really excited about this.
My game, SparkChess, has been approved in the AppStore: http://itunes.apple.com/app/sparkchess/id398133128
It really is amazing: the same application, using the same code with just minor tweaks is now available online for all browsers/platforms, as standalone application for Windows, Mac and Linux, on Android devices and now on iPad as well.
I can't really think of any other framework besides Flash/AIR with this kind of reach.
North America
Europe, Middle East and Africa
Asia Pacific