The puzzles are usually the difficult task to perform.... While it is in printable form, how can add the designing steps to make it effective? Share your ideas....!
I'm not sure how the pieces themselves are created ( i.e., number of pieces and their shapes ). But, a die needs to be created in order to cut the pieces out of a thick card stock. The picture itself is, obviously, a photograph that is printed on a coated sheet and laminated to the card stock. So, the puzzle itself can be a layered Illustrator file with a Placed photograph. Your die cut stamp needs to be on a separate layer. Like that, see?
Do you want to make crossword puzzles?
This will help you then.