I have just downloaded Digital Editions 1.8 for its accessibility options (my son has autism & can't read). I cannot get the speech function to work & there are no instructions other than the list of keyboard commands. Sue
Have you installed any screen reader? Such as JAWS (http://www.freedomscientific.com/jaws) or NVDA (http://www.nvda-project.org, which is open source software) on Windows, or enabling the Voice Over (Instructions here: http://www.apple.com/accessibility/voiceover) on Mac OS.
To enable Adobe Digital Editions (ADE) for use with screen readers, you need the JAWS or NVDA reader on Windows or VoiceOver reader on the Macintosh.