CHANGING THE INTERFACE COLOR SCHEME:
The Photoshop CS6 default interface is dark, but if you prefer the lighter interface you are used to from earlier versions,
you can change it back in the appearance area. There are 4 default color themes.
Mac Photoshop > Preferences > Interface
Windows Edit > Preferences > Interface
CONFIGURING LARGER FONTS:
For those who need larger fonts, you can also change the UI Font Size down in the type area.
Be sure to restart Photoshop to see the changes.
TURNING OFF THE APPLICATION FRAME
CS6 opens now by default in "Application Frame". You can go Window>Application Frame in the main meu and uncheck this