I just installed CS 5.5 Design Standard. I'm trying to change the default unit of measure in InDesign from picas to inches. When I do it with no document open (so it will stick as the default) ID crashes. I can change it when a doc is open, but that only changes things for that particular doc. I've tried deleting my preferences, but that doesn't help.
I think I figured this out. I installed a plug-in (Blatner Tools) meant for CS 5. Once I removed the plug-in files the program allowed the changes to preferences without crashing. Apparently there is an updated version of Blatner Tools. Had to find that out the hard way.
This suggests you're not running the latest version of CS5.5, 7.5.2. If you are, it should prevent you from installing incompatible plugins. But a bug in the original 7.5.0 release of CS5.5 mistakenly allowed incompatible plugins to run.