Ok this is what worked for me. Careful! You will lose all Adobe products, licenses, user settings and custom-anything!
So Make sure you have your license keys ready to go and backups of the important stuff.
And only do this if you understand the steps and that you might mess up big time! And I am not responsible for that
Uninstall Adobe CS3 with the provided uninstaller (Applications/Utilities/Adobe Installers/ ).
Uninstall any other Adobe product (all of them) which are not in the CS bundle, like Flex Builder, Lightroom... (usually comes with an uninstaller)
Go to Finder and Preferences.
Go to Advanced and set: When performing a search: Search the current folder.
Make sure it searches in "Library" and for "File-Name"!
In Finder go to the home folder of your user, click the Library-folder.
Search for "adobe" in the Library folder.
Careful, the plan is to delete anything adobe BUT not stuff that other applications use/need.
Go for the folders first and make sure the path to them does not include other applications.
Do not delete:
..../Application Support/AppShelf/vault/adobe xyz
You may delete:
and so forth.
Also search for "Flex", "Lightroom" or other applications you might have had installed.
Note: Usually, a lot of stuff with Flash and Macromedia shows up too. Keep those if they are Flash Player related.
Select Macintosh HD in the Finder and navigate to the Library folder.
Perform the same searches as above and delete (with careful reasoning) all the adobe stuff.
Empty the Trash.
You may now re-install from your product discs.