You might take a look at
Walter
Zorn's free tooltip utility, a really neat onMouseover
application that makes your tooltips look like popups, including
the use of links within them.
You can use it for text links or in combination with image
maps. So far, I'm using only the former, but I'll be using the
latter for some new, complex C# screens in our next version
release.
There are a few things that can trip you up, such as: all the
HTML inside the Javascript area (the
escape('Some text') portion) cannot have carriage returns;
and certain characters must be escaped with a backslash (such as
replacing double quotes with backslashed single quotes). However,
it's all explained quite well on his site. You can control
backgrounds, transparencies, images, placement, etc.
As Peter says, do all your testing in a scrub project before
going live in the real one.
Good luck,
Leon