I had Adobe on my computer but suddenly PDFs wouldn't open. I deleted Adobe from my hd and tried to reload it. The message I get is "Installation encountered errors. Failed to initialize." I have Firefox and Google Chrome. I've tried it from both and tried it with the brower closed but I always get the same message.
Uninstalling Adobe Reader was the first thing I did.
You may want to try the following:
Run this fix from Microsoft: http://support.microsoft.com/mats/Program_Install_and_Uninstall
Uninstall Reader using Add/Remove Programs
If you want to reinstall Reader, download it from http://get.adobe.com/reader/direct/