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I believe my issue may be the same as or similar to http://forums.adobe.com/thread/867133 , but I'm not able to post to that forum.
Running Acrobat 10.1.2 on a fully-patched Windows 7/64 Bit system (Office 2010/32 bit). Antivirus is eSet NOD32 4.0.437.0. I've been having this problem for several versions of Acrobat Pro.
Frequently, when I open a PDF, Acrobat shows the document and is responsive to user action (e.g. scrolling) for a few seconds, and then becomes completely unresponsive for 10-15 seconds, and then is usable again. This happens fairly consistently. Even if I already have Acrobat open, opening a new file causes the same behavior.
Many of the comments on this sort of problem suggest security settings might be an issue.I have tried disabling Enhanced security, disabling "automatically trust sites from my Win OS security zones", disabling "verify signatures when the document is opened", disabling "load security settings from a server", also done "clear remembered account information" for LiveCycle Rights Management. Further disabled everything in advanced settings under Windows Integration. None of these changes have any effect on my problem.
Any suggestions for how to troubleshoot?