Do you have a services-config.xml file? Usually channels are described in a config file, which includes options for creating a secure channel.
This page might have some useful info on it:
drkstr_1, thanks for the reply! Was starting to feel alone . Quoting from the link you sent me (which I had previously discovered when originally googling the issue) 'You can always use the HTTPService and WebService components instead of RemoteObject' - I am already using the WebService component built into the Flex 4.6 framework so I am not using the RemoteObject approach. Additionally, the flex application I am developing is a mobile app designed to be deployed to the various different app stores and it is calling into an ASP .NET webservice so I really don't see where a 'services-config.xml' file would fit into this equation at all...
Any other ideas?