Yes it is possible, no I can't tell you exactly how to do it,
it has
been too long for me. But in essence you use the Adobe FDF to
populate
PDF forms with data, and it is possible to use ColdFusion to
dynamically
create the FDF data.
You can also create PDF files on the fly, with some
limitations, within
the latest version of CF using <cfdocument...> tags.
But you would need
to recreate the PDF form inside of ColdFusion to use this
method at this
time.