Please help me understand.
I have 5 drives
2 raid 0 for video
2 other drives
Personally I'd break out the RAID 0. I don't consider them necessary unless you're working with Uncompressed HD (and even then a RAID 3 is still the better option). Plus there is the greater risk of data loss with a RAID 0.
So what I'd do is this.
G: Scratch (Previews, Media Cache, etc.)
Use your largest drive for E: and the smallest for C: