1 person found this helpful
In my experience it's impossible for the small guy to do runs of that size in-house and get the quality at a price even close to what a commercial shop can deliver. I have a $5,000 color laser here that I use pretty much just for proofing and really short run stuff like 100 business cards that I need the same day. My cost to operate it is higher than I pay my printer in most cases.
Commercial shops keep the equipment running all day which means they can lease it on favorable terms, and they can get better equipment than you or I can afford, and they can replace it when it becomes worn out or obsolete (which is the source for most of the equipment you'll find on the used market).
If the local guys won't help you out, start looking a little wider. There are a lot of printers out there, and they're all hungry.