What is the specific error message? I see many references (in searches) to problems with installs/updates that damaged the adobe install.
Are any of your other adobe apps throwing the same error?
Sorry, meant to paste that. I might have figured it out too. I have a Matrox MXO LE w/ MAX (ExpressCard) but it was not inserted as I currently don't need it. That said, it hasn't crashed since I launched with it plugged in. I shouldn't NEED it plugged in for this to work.
Problem Event Name: APPCRASH
Application Name: Adobe Encore.exe
Application Version: 220.127.116.11
Application Timestamp: 50438542
Fault Module Name: MSVCR100.dll
Fault Module Version: 10.0.40219.325
Fault Module Timestamp: 4df2bcac
Exception Code: 40000015
Exception Offset: 00000000000761c9
OS Version: 6.2.918.104.22.168.256.48
Locale ID: 1033
Additional Information 1: f207
Additional Information 2: f2078eda39829013f72f1646ce721a74
Additional Information 3: c693
Additional Information 4: c6933b15ad79b01377ec425d2766c234
I don't understand it either, but interference/changes from other hardware/software is one of the situations involved in similar errors. I suspect that an uninstall/clean/reinstall without the card might fix everything. But keeping the card in seems simpler! And I really don't know...
I see more of this issue in the Premiere forum.
I am having this problem too. Running Windows 7, 64-bit with 16GB Ram. A new install with the other Adobe CS6 programs working fine.
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After further reading, running as adminstrator (even though I'm in the adminstrator account) seems to do the trick!