its not listed in the official supported hardware. System requirements | Adobe Premiere Pro
any nvidia card with close to 1gb or more memory will usually work with newer versions of premiere. the fx 4600 base model lists 768mb, which may not let it work with premiere. that quadro is also extremely slow, not recommended for use with premiere.
The answer is:
Premiere Pro CS5 introduced MPE CUDA GPU acceleration - but it required 765MB of free, unused graphics RAM in order to even enable it at all. Unfortunately, the Quadro FX 4600 has only 768MB total of graphics RAM - but the Windows GUI itself eats up nearly 20MB of that RAM, leaving you with less than 750MB of free, unused RAM available.
Moreover, nVidia has been gradually phasing out driver support for the older GPUs. The most recent driver release for the Tesla-architecture GPUs, 341.81, is basically patches for a driver that's been released well over one year ago.
With those in mind, a system equipped with the Quadro FX 4600 will be permanently locked to the MPE software-only mode (no CUDA GPU acceleration whatsoever). And future versions of Premiere will require a newer version of OpenGL than the version supported in hardware by the older GPUs, so that future versions of Premiere may not run at all on a PC that's equipped with such older hardware.
Thanks for ur reply.
What if i install Quardo FX 4600 and GeForce 9600 GT (1GB) together in same PC. Will it work?
Maybe; maybe not. The 9600 GT is of the same GPU generation as that Quadro FX 4600, which means that CUDA GPU acceleration is iffy - and since the release of Premiere Pro CC 2014.2, the older Tesla-architecture GPUs such as the 9600 GT are now no longer supported for CUDA GPU acceleration. With newer releases of Premiere, you'll be permanently stuck in the MPE software-only mode with those particular GPUs no matter what.
What if i use an older version of Adobe Premiere like CS5 or CS6, Will it work with that?
There's no guarantee of such compatibility. Neither CS5 nor CS6 supports more than one GPU at a time for GPU acceleration. That means that only one of the GPUs can be used at all for GPU acceleration (in this case, that archaic, weakling 9600 GT), while the FX 4600 sits almost completely unused except for outputting to an auxiliary monitor.