If your application calls the specific help topic, and not
the WebHelp start page, you'll get the layout on the left (albeit
without the buttons). The topic will have a "Show" link which, when
clicked, reveals the Nav pane as in the layout on the right. (See
the "Show Navigation Pane Link in Topics" option in the second page
of the Generate wizard.)
You can configure that "Show" link to read "Show Navigation
Pane," if you prefer, and you can place it in a different location
than the default top right.
Good luck,
Leon