for the mesh, hexagon is actually better than photoshop. Since it can create the actual mesh. Though, you can import the mesh into photoshop so you can see it while you paint the texture.
The 3d creation portion of photoshop is still a bit limiting. (But my experience stops with CS5. I have not tried CS6 yet, so impovement could have been made)
The issue I have with hexagon is the amount of bugs in it. I prefer a more robust and more expensive alternative. But thats me
A free alternative is Blender. But I find the UI a bit outdated and hard to grasp. But again, thats me.
Generate your UV maps as you normally would then load them into photoshop and get painting. You may like other texture generating apps to go along with photoshop. Genetica is great for making tileable textures.
Thanks, this is very helpful. I feel the same abut hexagon. I guess my real question now is what product do I want to put the time into learning so I can make 3d clothing.
Like Silkrooster said, 3D creation in Photoshop right now is still pretty limiting. But it is great for importing the UV maps and painting textures on.
Are you talking about actually modelling an object (clothing) in 3D? If so I really recommend Autodesk Maya or Zbrush. They are both great 3D softwares that have indepth tools for modelling.