I'm testing InDesign CS6 under OS X 10.8. Seems to work without problems - except one thing which I noticed several times while working on a document (that I was working on under 10.7 as well, without problems):
I transform a group of objects (mostly placed Illustrator EPS) by dragging one corner of the group (with one or more modifier keys). After a few moments InDesign gets unresponsive (it freezes, cursore won't move, although you can change apps via Alt+Tab). Activity monitor shows 100% CPU usage (for one CPU core, at least). After a few seconds, everything goes back to normal.
Process analysis looks sth like that (it goes on and on like this):
This might be a problem related to this very document. On the other hand, this worked flawlessly under 10.7. So maybe someone at Adobe wants to look into that?
Stop using EPS and use native AI or PDF and see if that helps.
Thanks, I'll try that.
In the meanwhile, I opened another document that contains the same group of objects. No hangs here. So this might indeed be a problem related to the document itself.