AE 5 failed to start. "Unexpected failure during application start up".
We cannot know. You are not providing any relevant system information.
We need to know a lot more to help you. Please provide answers to the questions listed here: "FAQ: What information should I provide when asking a question on this forum?"
...and let me add my two cents, too: do you mean AE CS5, or do you actually mean AE5, which is five versions older?
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