I have been using CS5 and am about to install CS6. For my two cameras, I set up camera profiles and defaults by ISO in Camera Raw. The defaults include initial noise reduction settings for each ISO. Will these profiles and defaults transfer to CS6? If so, can I assume the noise reduction settings will be comparable? Thanks.
IIRC, all of those settings did transfer when I installed Photoshop CS6. But I installed CS6 first and then removed CS5. This broke the external editor link in Lightroom, forcing me to install Lightroom 4 again to reestablish the link.
It's likely that you will have to redo your default settings anyway using the PV 2012 adjustments because they are quite different in some respects. Noise reduction is improved in the new version, so I think you will probably want to reevaluate your default settings.