I am on Windows so have NO idea if any of these will help, but reading these saved links may point you in the right direction... especially the first 2 links about permission problems
Mac and Root User http://forums.adobe.com/thread/879931
Mac and Playback http://kb2.adobe.com/cps/842/cpsid_84287.html
Mac and 2 Monitors http://forums.adobe.com/thread/876566
Mac & nVidia Driver http://forums.adobe.com/thread/1075592
Okay I have a couple of questions for you.
How many hard drives are you using? (Please describe what each seperate disk is being used for currently)
What type of interface are your hard drives using?
Have you tried saving your projects to a different hard drive?
Although if what I'm understanding is correct it sounds like you're saying that you open up project "A" and it won't allow you to save. But then later on you'll open up "Project A" again and it will allow you to save and it's on the EXACT same hard drive and inside the exact same folder etc. Let me know if I'm understanding correctly.
My final question is have you tried to uninstall then reinstall and see if the problems are still there?
I am using 2 drives. I have my projects on one drive and my main drive has the application. Right now everything is defaulted to it's nomal spots. Yes, you are right in understanding that I will open up "Project A" work for a while, then I will save or auto-save will come up and it will freeze. I will open "Project A" again, work for a while, then I will save or auto-save will come up, and it will save just fine. There seemes to be some sticking point around a quarter of the progress back through that it always stops at. I know if it makes it past that point that it will save just fine. If it slows down there I hold my breath.
I'm having the same problem and desperately needing help, fast! I've been working on my premier project for a year now, I haven't encountered any problems like this before, until today.
I'm working on a 2009 Mac book pro, running mountain lion. Working off of an external LaCie rugged hard drive and using cs 6. When I try to save or when it auto saves, the first two times is usually fine. And then the third timer tries to save, it will freeze. It'll freeze premier pro, and my whole computer as well! I desperately need a quick resolution to this because the deadline for this project is due in two weeks.
Please any comments and feedback will help.
On a side note, I have looked around and found that some cs5 users have this problem as well, haven't found a solution for it. But they also have a related audio problem where their speakers will not work, they become muted and the speaker icon becomes greyed out.