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When you replaced the drive, how did you go about installing the OS and the programs - manually, or from an image, etc.?
I used the restore function available through Mac's Time Machine.
It looks like I've solved my problem.
I decided to try again - this time cloning my original drive onto the new one instead of using Time Machine - and now everything seems to work just fine. Just faster. I can only assume that in the restoration process the first time, some necessary files got corrupted or went missing. Thanks, Bill, it was your question that made me wonder whether it might be better to create an image.
I never trust Time Machine. I've had too many issues with it in the past.