Adobe Exchange CS6, unable to log me in...

Me too

This worked for me. (everything is pulled from this post here.)

Delete the opm.db file on your machine

• For Windows: C:\Documents and Settings\<username>\Local Settings\Application Data\Adobe\OOBE
• For Mac:  ~/Library/Application Support/Adobe/OOBE for Mac. (make sure you can view hidden files in Finder or delete it from your terminal using rm ~/Library/Application Support/Adobe/OOBE/opm.db)

After you delete the opm.db file, you will have to log in again and everything should work.

It's just really annoying and kind of strange that I can be logged into Folio Builder and logged in online, but Exchange still won't sign in properly. Welcome to the world of cloud computing.