I got this message that started just yesterday. This is on the heels of my F:/ projects drive issue (referenced here: http://forums.adobe.com/message/5013317#5013317).
Before doing what Windows 7 tells me, I thought I should check with you all to see how to handle this since I never encountered this before and do not know if it could be related to the projects drive issue.
Another note: I had my pagefile.sys on the F:/ drive. After the F:/ issue arose, Windows created another one automatically on C:/. I went into Advanced Setting and changed the Virtual Memory back to F:/, following one of Harm's recommended methods. No issues from it, but that's what I did.
With sincere thanks,
I would suggest running the CHKDSK utility and allow it to run at boot time. It may demand it.