I use a Mac Pro 2x2.66 Dual Core Xeon tower with 15 GB Ram and OS 10.7.5. CS6 (always the latest update) is becoming very "buggy". It starts slowing way down, then does things like sharpening changes in ACR disappear when the photo is opened as a file in Photoshop, and other random little failures. Resetting preferences in both Bridge and Photoshop doesn't fix it. The only thing that works is re-installing CS-6. I have to do this now about every two months, which is a pain. Any thoughts about what might be going on and how to fix it? Thanks!!
Sounds like some system caches or your swap file might have something to do with it, which on a Mac could point to a more generic system issue. Seems to me that either your program is causing excessive logging because it throws a lot of tiny errors or something with the system's optimization stuff (prefetch caches and al lthat) is going wrong. Eventualyl that stuff will fill up and prevent your system from working better. I'm by no means a Mac expert, but I'd start by diagnosing your system with tools like OnyX and similar, Repair Permissions and the usaul steps... Also check your system log files.