Where are you clicking? In the layers panel or in the main image window with the move tool?
I am clicking in the main image window. I can select layers in the layers panel but when I go to move them they disappear.
If you move a layer below a layer with no transparency in it--i.e., the whole layer is opaque, it will disappear since what's on top covers what's below it. If that's not what's happening, try deleting the preferences: quit the editor, then restart it while holding down ctrl+alt+shift (command+option+shift on a mac), and keep the keys down till you see a window asking if you want to delete the settings file. You do.