What version of InDesign and what Operating System and specs of your computer?
Microsoft Windows XP
You can remove minor corruptions from a file by exporting to .inx
File>Export and choose Adobe Interchange (INX)
Open this file and it opens as "untitled"
You should also try trashing your preferences.http://forums.adobe.com/thread/526990
There's pretty good chance you have a bad image or graphic on a page someplace, too.
Can you epxort the file in two halves? If you can, it's just too complex for your system resources (You may well be running out of memory since ID can address only a bit less than 4 gb of RAM and needs to use disk space for virual memory -- older systems tend to have drives with less free space and a lot of fragmentation). If one half crashes, divide that in half and try exportin each of those halves. Repeat until you isolate a problem page.