What version of InDesign? How did you install InDesign? What computer platform? Has it ever worked for you, or did it stop working?
on a Mac OS x 10.6.8 CS5 has worked fine Installed from a CD
Do you get a crash report? If so, please post it on Pastebin.com and put a link to it here.
Have you tried replacing your preferences? See Replace Your Preferences
Also, does it work in a new user on your Mac?