As Kevin sez, this is not at all typical.
If you gave a bit more information regarding the nature of your Timeline
when you are adding the Adjustment Layer (media type(s),
number of layers, effects added to individual clips, etc.),
someone might be able to help.
A screenshot of your Timeline often helps as well.
ok in the adjustment layer i'm using red giant denoiser ll and a compound arithmatic.
after alppying the layer, whether or not i've added the effects, the program monitor freezes and i'm unable to save by either command S or quitting and saving.
i am able to continue working in other parts of the program, i.e. switching tracks on/off, applying and manipulating effects, but dbl clicking clips in the timeline will not bring them up in the source monitor.
it seems that anything regarding a video image is frozen.
bug report sent
Sorry I dont know the answer to your issue..but I am curious about all the long Black Video Clips in Vid Layer 2. Looks like your movie is 50% black.