I'm running After Effects among the Adobe Production Premium CS6 product line on a top-of-the-line brand new iMac with latest OSX (10.8.4)
THIS IS JUST CRAZY! How much does this software cost? And it won't even open??? Unacceptable. I'm losing a client right now as we speak
It may not be Adobe's fault. I've seen this when there is a problem accessing a 3rd party plug-in during AE initialization. Have you recently installed a plug-in? Check the plug-ins folder for anything suspicious:
Macintosh HD>Library>Application Support>Adobe>Common>Plugins>CS6 >Mediacore>
If you need help urgently, you should contact Adobe Technical Support, not post to a forum where people help out in their free time.