This is a known issue that we're working with Google to resolve. Here are some steps that have helped some users work around this problem.
1. Exit chrome, make sure it is not running
2. using file explorer go to c:\users\<user name>\appdata\local\google\chrome\user data\pepperflash
3. Delete the folders you see there
4. Start chrome again, it should work now.
<user_name> is your logon name.