From this doc http://helpx.adobe.com/x-productkb/policy-pricing/configuration-error-cs5.html it appears it is a permissions problem.
Also, read this and see if you can find anything helpful. http://forums.adobe.com/thread/1218272
A quick way that worked for me as a Mac user when I ran into this, was to open Terminal and run this command.
sudo chmod -R 777 /Library/Application\ Support/Adobe