Running IE 10 (Latest), Flash 11 (Latest), Windows 7 Premium. IE will play flash but also warn that flash needs to be updated/installed at the same time. This doesn't happen with other browsers tho. I have tried uninstalling and reinstalling flash but it does not help. The browser doesn't seem to be reporting that flash is installed, even tho it is and flash does work on flash enabled sites. In IE add-ons flash and shockwave are uptodate and enabled. All other add-ons have been disabled.
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Did you try disabling ActiveX Filtering for IE 10 ?
Launch IE 10
On Right Hand Top, you have multiple buttons
Click on Tools -> Security -> Make sure there is no Tick on "ActiveX Filtering"
If there is a tick, click on it (ActiveX Filtering)
Close IE 10 and launch it again.