I have been struggling with color issues with my imac for years. I found a way to avoid it looking different when I send my images to the web. I have to edit in ps the way i know it will look on the web. but today i got a new imac. i thought that would fix it all , but no luck the color is still off between the image i put on my computer, cs5, the monitor and the web. please help!! maybe i have the incorrect settings!
using sRGB everywhere? that should help
..and make sure the sRGB profile is embedded in the file (Save For Web strips the profile by default).
If the profile is not embedded, Safari will not color manage the image and it will look different from Photoshop (which does).