Without knowing anything about your work it is impossible to judge these things specifically. Generally I'd say you are hopelessly overdoing it with the GPU. I don't know a single use case that actually uses 4 GB on any graphics card except for games. Most OpenGL plug-ins in AE are limited to 2 GB and while this of course could change in the future, currently I see no realistic scenario to push it beyond that, because in most cases then the plug-ins will simply crash due to bugs or their internal logic not being able to deal with more VRAM. Likewise you will see zero benefit of this in C4D unless you use a GPU third-party renderer like Octane. C4D's OpenGL performance will collapse on itself long before you have filled all the memory with textures... Similarly, I see no advantage of 64GB RAM over 32GB. I do heavy CAD scenes all the time, but still have enough room left on my systems with 24 and 32GB, respectively. AE won't use that much RAM even with all MP settings at full on most projects as well. Having the fastest CPU is another matter and many functions in AE, PS and C4D are of course pur CPU and will work faster on a faster processor. With regards to the cache stuff, scroll down a few posts and make up your mind...
Thank you a lot Myllenium.
II thought to buy 64 Go RAm because some AE users wrote on forums this si helpful.
I will search the post relating to the AE cache